Journal of South Asian Association of Pediatric Dentistry

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VOLUME 5 , ISSUE 1 ( January-April, 2022 ) > List of Articles


Nitrous Oxide Oxygen Inhalation as Safe and Effective Tool for Behavior Management in Pediatric Dentistry

Jatinder K Dhillon, Gauri Kalra, Vijay Prakash Mathur

Keywords : Anxiolysis, Nitrous oxide analgesia, Pharmacological behavior management

Citation Information : Dhillon JK, Kalra G, Mathur V P. Nitrous Oxide Oxygen Inhalation as Safe and Effective Tool for Behavior Management in Pediatric Dentistry. J South Asian Assoc Pediatr Dent 2022; 5 (1):1-2.

DOI: 10.5005/jp-journals-10077-3221

License: CC BY-NC 4.0

Published Online: 29-03-2022

Copyright Statement:  Copyright © 2022; The Author(s).


  1. Bhandari R, Thakur S, Singhal P, et al. Parental awareness, knowledge, and attitude toward conscious sedation in North Indian children population: a questionnaire-based study. Indian J Dent Res 2018;29(5):693–697. DOI: 10.4103/ijdr.IJDR_120_17
  2. Hallonsten AL, Jensen B, Raadal M, et al. EAPD guidelines on sedation in paediatric dentistry. European Academy of Paediatric Dentistry: http://www eapd gr/dat/5CF03741/file pdf Stand. 2013;7:12. Accessed on January 5 2022
  3. Coté CJ, Wilson S American Academy of Pediatrics; American Academy of Pediatric Dentistry. Guidelines for monitoring and management of pediatric patients before, during, and after sedation for diagnostic and therapeutic procedures. Pediatrics 2019;143:e20191000. DOI: 10.1542/peds.2019-1000
  4. Gillman MA. Mini-review: a brief history of nitrous oxide (N2O) use in neuropsychiatry. Curr Drug Res Rev 2019;11(1):12–20. DOI: 10.2174/1874473711666181008163107
  5. Breitman F. Psychology does half the work in nitrous oxide analgesia. Dent surv 1951;27:1081–1085
  6. Holst JJ. Use of nitrous oxide oxygen analgesia. Int dent J 1962;12:47–54
  7. Langa, H. Relative Analgesia in Dental Practice. Philadelphia, W.C. Saunders Co., 1968.
  8. Attri JP, Sharan R, Makkar V, et al. Conscious sedation: emerging trends in pediatric dentistry. Anesth Essays Res 2017;11(2):277–281. DOI:10.4103/0259-1162.171458
  9. Heinrich M, Menzel C, Hoffmann F, et al. Self-administered procedural analgesia using nitrous oxide/oxygen (50:50) in the pediatric surgery emergency room: effectiveness and limitations. Eur J Pediatr Surg 2015;25(3):250–256. DOI: 10.1055/s-0034-1371716
  10. Galeotti A, Garret Bernardin A, D'Antò V, et al. Inhalation conscious sedation with nitrous oxide and oxygen as alternative to general anesthesia in precooperative, fearful, and disabled pediatric dental patients: a large survey on 688 working sessions. VBiomed Res Int 2016;2016:7289310. DOI: 10.1155/2016/7289310
  11. Zier JL, Liu M. Safety of high-concentration nitrous oxide by nasal mask for pediatric procedural sedation: experience with 7802 cases. Pediatr Emerg Care 2011;27(12):1107–1112. DOI: 10.1097/PEC.0b013e31823aff6d
  12. Pedersen RS, Bayat A, Steen NP, et al. Nitrous oxide provides safe and effective analgesia for minor paediatric procedures–a systematic review. Dan Med J 2013;60(6):A4627. PMID: 23743110.
  13. Guidance For Infection Control and Sterilization of Porter and MatrxNitrous Oxide and Oxygen System Components: Available online at: Accessed on January 6, 2022
  14. Available online at: Accessed on January 10, 2022
  15. Available online at: Accessed on January 6, 2022
  16. Ferrazzano F, Quaraniello M, Sangianantoni G, et al. Clinical effectiveness of inhalation conscious sedation with nitrous oxide and oxygen for dental treatment in uncooperative paediatric patients during COVID-19 outbreak. Eur J Paediatr Dent 2020;21(4):277–282. DOI: 10.23804/ejpd.2020.21.04.4
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