Aim: An exponential increase in the prevalence of autism spectrum disorder (ASD) has been observed in India in recent years, which is a huge source of concern in terms of treatment planning and patient management. The aim of the present study is to evaluate the awareness and perception of Indian pediatric dentists and postgraduates regarding the diagnosis and management of patients with ASD. Study design: The questionnaire-based study was completed by 602 pediatric dentists and postgraduates in order to gauge their level of awareness and perception of the diagnosis and treatment of patients with ASD. The study's analysis of the data made use of inferential statistics. Results: The majority of the participants demonstrated a fair knowledge of the characteristic features of ASD, yet only 37.3% of the participants were aware of its prevalence in India. About 83% of pediatric dentists and 93% of postgraduates would prefer to take continuing education programs for the diagnosis and management of ASD patients. Conclusion: The results indicate an alarming dearth of knowledge and awareness regarding the diagnosis and management of ASD in postgraduates in comparison to pediatric dentists. ASD is the most common neurodevelopmental disorder (NDD). Hence, it is extremely important to improve our diagnostic skills and provide a customized treatment plan that caters to their individual needs through additional educational programs at the postgraduate level.