Journal of South Asian Association of Pediatric Dentistry

Register      Login

VOLUME 5 , ISSUE 1 ( January-April, 2022 ) > List of Articles

ORIGINAL RESEARCH

Cavity Disinfection with Herbal Disinfectants Licorice (Mulethi) and Munident Tablets in Children Aged 5–9 Years: A Randomized Controlled Trial

Disha Kapil, Priya Mendiratta, Bhavna G Saraf, Neha Sheoran, Gauri Kalra, Pooja Srivastava, Sakshi Kataria

Keywords : Antibacterial, Ayurveda, Herbal, Licorice, Munident

Citation Information : Kapil D, Mendiratta P, Saraf BG, Sheoran N, Kalra G, Srivastava P, Kataria S. Cavity Disinfection with Herbal Disinfectants Licorice (Mulethi) and Munident Tablets in Children Aged 5–9 Years: A Randomized Controlled Trial. J South Asian Assoc Pediatr Dent 2022; 5 (1):38-43.

DOI: 10.5005/jp-journals-10077-3222

License: CC BY-NC 4.0

Published Online: 29-03-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Background: Dental caries is still a foremost oral health issue affecting the population in developing countries. Many anticariogenic synthetic therapeutic agents have been used as cavity disinfectants, but with the rise in bacterial resistance, there is substantial concentration and an emergent trend in herbs and homeopathy. Aim: This study compared the antibacterial efficacy of natural herbal agent licorice, commercially available Ayurvedic agent Munident tablets 500 mg, and normal saline as a cavity disinfectant. Materials and methods: In this present study, two test groups were included, group I (licorice), group II (Munident crushable tablets), and group III (Normal Saline) was included as a control group. The children were randomly divided into 15 for each group with a cariogenic cavity not having any deep dental caries, pulp pathology, or any other intraoral pathology without systemic conditions. Two samples were collected by excavating cariogenic dentine predisinfection. After disinfection, the cavity with test agents, after collecting the samples sent to the microbiological laboratory of college for a total viable count of bacteria. The collected data were statistically analyzed with the Kruskal Wallis Test, Mann-Whitney U test, and suing Wilcoxon paired t-test. Result: This study showed a statistically significant reduction in total viable count compared to pre and postdisinfection with test agents. Munident Crushable tablets were most effective amongst all the groups, whereas licorice has also displayed statistically significant results. Conclusion: Ayurveda and herbal products can be effectively used as cavity disinfectants, helping eradicate the bacteria and diminishing secondary caries with longevity and success of the restoration.


PDF Share
  1. Ratledge DK, Kidd EA, Beighton D. A clinical and microbiological study of approximal carious lesions. Part 2: efficacy of caries removal following tunnel and class II cavity preparations. Caries Res 2001;35(1):8–11. DOI: 10.1159/000047424
  2. De Almeida Neves A, Coutinho E, Cardoso MV, et al. Current concepts and techniques for caries excavation and adhesion to residual dentin. J Adhes Dent 2011;13(1):7–22. DOI: 10.3290/j.jad.a18443
  3. Bin-Shuwaish MS. Effects and effectiveness of cavity disinfectants in operative dentistry: a literature review. J Contemp Dent Pract 2016;17(10):867–879. DOI: 10.5005/jp-journals-10024-1946
  4. Bowen WH, Koo H. Biology of streptococcus mutans derived glucosyl transferases: role in extracellular matrix formation of cariogenic biofilms. Caries Res 2011;45(1):69–86. DOI: 10.1159/000324598
  5. Foley J, Blackwell A. In vivo cariostatic effect of black copper cement on carious dentine. Caries Res 2003;37(4):254–260. DOI: 10.1159/000070867
  6. Weerheijm KL, Groen HJ. The residual caries dilemma. Community Dent Oral Epidemiol 1999;27(6):436–441. DOI: 10.1111/j.1600-0528.1999.tb02045.x
  7. Van Amerongen WE. Dental caries under glass ionomer restorations. J Public Health Dent 1996;56(3 Spec No):150–154. DOI: 10.1111/j.1752-7325.1996.tb02426.x
  8. Brännström M, Nyborg H. Cavity treatment with a microbiocidal fluoride solution: growth of bacteria and effect on pulp. J Prosthet Dent 1973;30(3):303–310. DOI: 10.1016/0022-3913(73)90187-x
  9. Thosar N, Basak S, Bahadure RN, et al. Antimicrobial efficacy of five essential oils against oral pathogens: An in vitro study. Eur J Dent 2013;7(Suppl 1):S71-S77. DOI: 10.4103/1305-7456.119078
  10. Prabuseenivasan S, Jayakumar M, Ignacimuthu S. In vitro antibacterial activity of some plant essential oils. BMC Complement Altern Med 2006;6:39. DOI: 10.1186/1472-6882-6-39
  11. Dalirsani Z, Aghazadeh M, Adibpour M, et al. In vitro comparison of the antimicrobial activity of ten herbal extracts against streptococcus mutans with chlorhexidine. J Appl Sci 2011;11(5):878–882. DOI: 10.3923/jas.2011.878.882
  12. Sharififar F, Moshafi MH, Mansouri SH, et al. In vitro evaluation of antibacterial and antioxidant activities of the essential oil and methanol extract of endemic zataria multiflora boiss. Food Control 2007; 18(7):800–805. DOI: https://doi.org/10.1016/j.foodcont.2006.04.002
  13. Patri G, Sahu A. Role of herbal agents-tea tree oil and aloe vera as cavity disinfectant adjuncts in minimally invasive dentistry-an in vivo comparative study. J Clin Diagn Res 2017;11(7):DC05–DC09. DOI: 10.7860/JCDR/2017/27598.10147
  14. Shetty RN, Shetty SB, Janardhanan S, et al. Comparative evaluation of effect of use of toothbrush with paste and munident on levels of Streptococcus mutans and gingival health in children: an in vivo study. J Indian Soc Pedod Prev Dent 2017;35(2):162–166. DOI: 10.4103/JISPPD.JISPPD_265_16
  15. Hu CH, He J, Eckert R, et al. Development and evaluation of a safe and effective sugar-free herbal lollipop that kills cavity-causing bacteria. Int J Oral Sci 2011;3(1):13–20. DOI: 10.4248/IJOS11005
  16. Isbrucker RA, Burdock GA. Risk and safety assessment on the consumption of Licorice root (Glycyrrhiza sp.), its extract and powder as a food ingredient, with emphasis on the pharmacology and toxicology of glycyrrhizin. Regul Toxicol Pharmacol 2006;46(3):167–192. DOI: 10.1016/j.yrtph.2006.06.002
  17. Segal R, Pisanty S, Wormser R, et al. Anticariogenic activity of liquorice and glycyrrhizine I: inhibition of in vitro plaque formation by streptococcus mutans. J Pharm Sci 1985;74(1):79–81. DOI: 10.1002/jps.2600740121
  18. Godbole E, Tyagi S, Kulkarni P, et al. Efficacy of liquorice and propolis extract used as cavity cleaning agents against streptococcus mutans in deciduous molars using confocal microscopy: an in vitro study. Int J Clin Pediatr Dent 2019;12(3):194–200. DOI: 10.5005/jp-journals-10005-1620
  19. Jain E, Pandey RK, Khanna R. Liquorice root extracts as potent cariostatic agents in pediatric practice. J Indian Soc Pedod Prev Den 2013;31(3):146–152. DOI: 10.4103/0970-4388.117964
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.